University Clinic Bonn Institute of Experimental Haematology and Transfusion Medicine Director: Prof. Dr. Johannes Oldenburg
Institute

Contact Address

Institute of Experimental Haematology
and Transfusion Medicine
University Clinic Bonn
Sigmund-Freud-Str. 25
D-53127 Bonn
Germany

Director: Prof. Dr. J. Oldenburg

Tel.: +49-(0)228-287-5175
Fax.: +49-(0)228-287-4783





Structure of the Institute


Center of Haemostasis and Thrombosis

  • Haemophilia Center (1500 patients with bleeding disorders)
  • Thrombophilia Center (2000 outpatients a year)
  • Blood Coagulation Laboratory (phenotyping) Unit
  • Molecular Haemostasis (genotyping) Unit


Center of Transfusion Medicine

  • Blood Donor Unit
  • Production Unit of Blood Components including testing for  Blood Transmitted Disorders
  • Immunhaematology Unit
  • HLA diagnostic
  • Stem cell unit 

 





Scientific focus

  • Characterization of proteins involved in the Vitamin K Cycle
  • Pharmacokinetic and pharmacodynamic of coumarin action and metabolism
  • Phenotype-genotype correlation of inherited coagulation disorders focussing on haemophilia, FXIII and the vitamin K cycle
  • Pathophysiology and diagnostic tools in inherited and acquired  thrombophilias
  • Haemophilia B gene therapy
  • Epitope mapping of FVIII inhibitors 
  • Haemotherapy of alloimmunocytopenias during the pre- and perinatal period.
  • Haemotherapy in Transplantation Medicine
  • Expression profiling in platelets
  • Molecular mechanisms of thrombin generation and regulation